ANA Differentiator Panel

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General Information

Lab Name
ANA Differentiator Panel
Lab Code
ANADP
Epic Ordering
ANA Differentiator Panel
Description

Initial screen includes ANA screen by IFA and by multiplex (ANARC). The multiplex screen detects the following antibodies: anti chromatin, ribosomal P, Sm, Sm/RNP, RNP, SSA/Ro, SSB/La, Centromere B, Scl70, and Jo1.

If either screening test is positive, identification panel ANARC2 will be performed at an additional charge.

If the multiplex screen is not positive and the ANA by IFA has a pattern consistent with anti-DFS70, ANARC4 will be added at a additional charge.

Synonyms
ADFS70, ANA Cascade, ANA Comprehensive Plus Panel, ANARC
Components

Interpretation

Method

IFA and multiplex immunoassay

Reference Range
See individual components
Interferences and Limitations

Grossly hemolyzed or lipemic serum may produce increased nonspecific background staining of substrate.

Guidelines

Ordering & Collection

Specimen Type
Blood
Collection

6 mL blood in a RED TOP or GOLD SST tube

Handling Instructions

Centrifuge and separate serum within 2 hours of collection. Refrigerate serum (only one aliquot needed).

Stability: Room Temperature: up to 8 hours; Refrigerated: 14 days; Frozen at -20°C or colder: Long Term

Quantity
requested: 2 mL serum
minimum: 1.5 mL serum

Processing

Processing

Centrifuge and separate serum within 2 hours of collection. Refrigerate serum (only one aliquot needed).

Stability: Room Temperature: up to 8 hours; Refrigerated: 14 days; Frozen at -20°C or colder: Long Term

Performance

LIS Dept Code
Performing Location(s)
UW-MT Immunology
206-520-4600

Clinical Lab, Room NW220,
University of Washington Medical Center,
1959 NE Pacific street, Seattle, WA 98195
Frequency
Monday-Friday, Negative ANA by IFA results same day. Positive results, reflex tests within 2 weeks.
Available STAT?
No

Billing & Coding

CPT codes
86038
LOINC
18727-8
Interfaced Order Code
UOW3234