Roche Platform Transition

This page compares reference ranges between the Roche and Beckman platforms for the selected category of tests. For a description of the transition from the Bechman to Roche automated chemistry platform, please see the Roche Transition guideline.

All BMP Liver Kidney Misc

Method Comparison

The slope of the linear regression of Roche onto Beckman represents the proportional bias between the two methods (i.e., the proportional change going from Beckman to Roche). The mean bias is expressed as a % or an absolute bias depending on whether there is a proportional bias between Beckman and Roche or a constant bias. A positive mean bias means that Roche results are higher than Beckman results, on average. While it is not recommended to use this information to convert one result directly to the other, the data will help when comparing results across platforms.

Tests with significantly different performance characteristics are reported using different component names and are not trendable in Epic.

Test Name	Beckman Code	Roche Code	Same code/Trendable?	Mean Bias	Slope of the Linear Regression (Roche vs. Beckman)	Coefficient of Determination (R²)
Albumin	ALB	ALB	✅	-2.7%	0.92	1.00
Alkaline Phosphatase (Total)	ALK	ALK	✅	5.3%	1.03	0.99
ALT (GPT)	ALT	ALTRD	❌	38%	1.22	1.00
AST (GOT)	AST	ASTRD	❌	36%	1.30	1.00
Bilirubin (Total)	BIL	BILRD	❌	-21%	0.89	0.99
Bilirubin (Direct)	BILD	BILDRD	❌	0.1 mg/dL	1.11	0.95
Urea Nitrogen	BUN	BUN	✅	-3.3%	0.98	1.00
Calcium	CA	CA	✅	-0.09 mg/dL	0.95	0.99
Chloride	CL	CL	✅	-2.15 mEq/L	1.01	1.00
Carbon Dioxide	CO2	CO2	✅	-3.2%	0.85	0.95
Creatinine	CRE	CRE	✅	0.02 mg/dL	0.98	1.00
Anion Gap	IGAP	IGAP	✅	2.9 units	1.01	0.94
Potassium	K	K	✅	0.06 mEq/L	0.99	1.00
Lactate Dehydrogenase	LD	LDRD	❌	18%	1.20	0.99
Magnesium	MG	MG	✅	4.1%	0.97	0.93
Sodium	NA	NA	✅	<0.2 mEq/L	0.99	1.00
Phosphate	P	P	✅	-0.16 mg/dL	0.99	0.99
Protein (Total)	TP	TPRD	❌	-1.0%	0.99	1.00
Uric Acid	URIC	URIC	✅	-3.7%	0.98	1.00

Reference Ranges

Name

Beckman

Roche

Albumin

Name: Albumin
Mnemonic: ALB
Units: g/dL
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	3.5-5.2	0-	3.5-5.2	0-	3.5-5.2

Effective date: 03/01/2015

Name: Albumin
Mnemonic: ALB
Units: g/dL
Method Code: PENPU1

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	3.9-5.2	0-	3.9-5.2

Effective date: 12/10/2025

Alkaline Phosphatase (Total)

Name: Alkaline Phosphatase (Total)
Mnemonic: ALK
Units: U/L
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-9y	111-281	0-9y	115-324
10y-11y	132-366	10y-11y	115-324
12y-13y	89-285	12y-13y	119-426
14y-17y	43-226	14y-17y	72-400
18y-24y	26-98	18y-24y	42-136
25y-34y	25-100	25y-34y	35-109
35y-44y	25-112	35y-44y	36-122
45y-54y	34-121	45y-54y	39-139
55y-64y	31-132	55y-64y	37-159
65y-74y	38-172	65y-74y	36-161
75y-199y	49-199	75y-199y	52-227
200y-	36-122	200y-	36-122

Effective date: 04/02/2015

Name: Alkaline Phosphatase (Total)
Mnemonic: ALK
Units: U/L
Method Code: PENPU1

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	35-104	0-	40-129	0-	40-104

Effective date: 12/16/2025

ALT (GPT)

Name: ALT (GPT)
Mnemonic: ALT
Units: U/L
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	7-33	0-49y	10-64
		50y-	10-48

Effective date: 03/01/2015

Name: ALT (Roche)
Mnemonic: ALTRD
Units: U/L
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	0-43	0-	0-63

Effective date: 12/12/2025

AST (GOT)

Name: AST (GOT)
Mnemonic: AST
Units: U/L
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	9-38	0-	9-38	0-	9-38

Effective date: 03/01/2015

Name: AST (Roche)
Mnemonic: ASTRD
Units: U/L
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	0-35	0-	0-50	0-	0-35

Effective date: 01/12/2026

Bilirubin (Total)

Name: Bilirubin (Total)
Mnemonic: BIL
Units: mg/dL
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-29d	0.2-1.3	0-29d	0.2-1.3	0-29d	0.2-1.3
1m-	0.2-1.3	1m-	0.2-1.3	1m-	0.2-1.3

Effective date: 03/01/2015

Name: Total Bilirubin (Roche)
Mnemonic: BILRD
Units: mg/dL
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-29d	0.0-0.9	0-29d	0.0-0.9	0-29d	0.0-0.9
1m-	0.0-1.1	1m-	0.0-1.1	1m-	0.0-1.1

Effective date: 12/17/2025

Bilirubin (Direct)

Name: Bilirubin (Direct)
Mnemonic: BILD
Units: mg/dL
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	0.0-0.3	0-	0.0-0.3	0-	0.0-0.3

Effective date: 03/01/2015

Name: Direct Bilirubin (Roche)
Mnemonic: BILDRD
Units: mg/dL
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	0.0-0.4	0-	0.0-0.4	0-	0.0-0.4

Effective date: 01/12/2026

Urea Nitrogen

Name: Urea Nitrogen
Mnemonic: BUN
Units: mg/dL
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	8-21	0-	8-21	0-	8-21

Effective date: 03/01/2015

Name: Urea Nitrogen
Mnemonic: BUN
Units: mg/dL
Method Code: PENPU1

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	6-20	0-	6-20

Effective date: 12/10/2025

Calcium

Name: Calcium
Mnemonic: CA
Units: mg/dL
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	8.9-10.2	0-	8.9-10.2	0-	8.9-10.2

Effective date: 03/01/2015

Name: Calcium
Mnemonic: CA
Units: mg/dL
Method Code: PENPU1

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	8.8-10.2	0-	8.8-10.2

Effective date: 12/09/2025

Chloride

Name: Chloride
Mnemonic: CL
Units: mEq/L
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	98-108	0-	98-108	0-	98-108

Effective date: 03/01/2015

Name: Chloride
Mnemonic: CL
Units: mEq/L
Method Code: PENPU1

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	98-107	0-	98-107

Effective date: 12/10/2025

Carbon Dioxide, Total

Name: Carbon Dioxide, Total
Mnemonic: CO2
Units: mEq/L
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	22-32	0-	22-32	0-	22-32

Effective date: 03/01/2015

Name: Carbon Dioxide, Total
Mnemonic: CO2
Units: mEq/L
Method Code: PENPU1

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	22-29	0-	22-29

Effective date: 12/10/2025

Creatinine

Name: Creatinine
Mnemonic: CRE
Units: mg/dL
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-17y	0.20-1.10	0-17y	0.20-1.10
18y-	0.38-1.02	18y-	0.51-1.18

Effective date: 03/01/2015

Name: Creatinine
Mnemonic: CRE
Units: mg/dL
Method Code: PENPU1

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	0.50-1.00	0-	0.70-1.20	0-	0.50-1.00

Effective date: 12/12/2025

Anion Gap

Name: Anion Gap
Mnemonic: IGAP
Units: not defined
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	4-12	0-	4-12	0-	4-12

Effective date: 03/01/2015

Name: Anion Gap
Mnemonic: IGAP
Units: not defined
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	4-12	0-	4-12	0-	4-12

Effective date: 03/01/2015

Potassium

Name: Potassium
Mnemonic: K
Units: mEq/L
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	3.6-5.2	0-	3.6-5.2	0-	3.6-5.2

Effective date: 03/01/2015

Name: Potassium
Mnemonic: K
Units: mEq/L
Method Code: PENPU1

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	3.5-5.1	0-	3.5-5.1

Effective date: 11/27/2025

Lactate Dehydrogenase

Name: Lactate Dehydrogenase
Mnemonic: LD
Units: U/L
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	<210	0-	<210	0-	<210

Effective date: 03/01/2015

Name: Lactate Dehydrogenase (Roche)
Mnemonic: LDRD
Units: U/L
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	0-225	0-	0-225

Effective date: 12/17/2025

Magnesium

Name: Magnesium
Mnemonic: MG
Units: mg/dL
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	1.8-2.4	0-	1.8-2.4	0-	1.8-2.4

Effective date: 03/01/2015

Name: Magnesium
Mnemonic: MG
Units: mg/dL
Method Code: PENPU1

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	1.6-2.6	0-	1.6-2.6

Effective date: 11/27/2025

Sodium

Name: Sodium
Mnemonic: NA
Units: mEq/L
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	135-145	0-	135-145	0-	135-145

Effective date: 03/01/2015

Name: Sodium
Mnemonic: NA
Units: mEq/L
Method Code: SAU400

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	136-145	0-	136-145	0-	136-145

Effective date: 02/06/2007

Phosphate

Name: Phosphate
Mnemonic: P
Units: mg/dL
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-11y	4.5-6.0	0-11y	4.5-6.0	0-11y	4.5-6.0
12y-	2.5-4.5	12y-	2.5-4.5	12y-	2.5-4.5

Effective date: 03/01/2015

Name: Phosphate
Mnemonic: P
Units: mg/dL
Method Code: PENPU1

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	2.5-4.5	0-	2.5-4.5

Effective date: 12/10/2025

Protein (Total)

Name: Protein (Total)
Mnemonic: TP
Units: g/dL
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	6.0-8.2	0-	6.0-8.2	0-	6.0-8.2

Effective date: 03/01/2015

Name: Total Protein (Roche)
Mnemonic: TPRD
Units: g/dL
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	6.4-8.3	0-	6.4-8.3	0-	6.4-8.3

Effective date: 01/12/2026

Uric Acid

Name: Uric Acid
Mnemonic: URIC
Units: mg/dL
Method Code: default

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	2.6-6.8	0-	3.9-7.6

Effective date: 03/01/2015

Name: Uric Acid
Mnemonic: URIC
Units: mg/dL
Method Code: PENPU1

Female		Male		Unknown
Age	Range	Age	Range	Age	Range
0-	2.4-6.2			0-	2.4-6.2

Effective date: 12/09/2025