Maternal Cell Contamination Comparator

General Information

Lab Name: Maternal Cell Contamination Comparator
Lab Code: MCCOMP
Epic Ordering: Maternal Cell Contamination Comparator
Description: This test is for the comparator sample used to evaluate fetal tissue for contamination by maternal cells. It usually consists of a tube of whole blood from the mother; saliva and extracted DNA are also accepted.

Both this test and Maternal Cell Contamination, Fetal [MCC] must be ordered in order for the laboratory to perform maternal cell contamination studies.

See Maternal Cell Contamination, Fetal [MCC] for more information.
Synonyms: amniocyte contamination, control, DNA fingerprinting, fetal testing, Maternal Cell Contamination, MCC studies, prenatal testing

Specimen Type: Blood, extracted DNA, or saliva
Collection: Whole blood:
5 mL LAVENDER TOP tube.
Also acceptable: YELLOW TOP (ACD) tube.

Unacceptable: Heparin green top tubes.

Extracted DNA:
1 ug (concentration >10 ng/uL).

Saliva:
Contact laboratory for validated collection kit.
Forms & Requisitions: Due to the complexity of prenatal testing, consultation with the laboratory is required.

Please contact the Genetics lab by e-mail (genelab@uw.edu) or phone (206-598-1149).

Outside providers: Genetics Requisition.

UW, HMC, and FHCC providers: Place order in Epic.
Handling Instructions: Whole blood: Refrigerate up to 1 week.

Extracted DNA: Frozen is preferred. Refrigerated is acceptable.

Saliva: Contact laboratory for a validated collection kit. Keep at room temperature.

Outside Laboratories
Whole blood: Ship at ambient temperature for receipt within 1 week of specimen collection.

Extracted DNA: Ship on a cold pack.

Saliva: Contact laboratory for a validated collection kit. Ship at room temperature.
Quantity: requested: Entire specimen.
minimum: Blood: 1 mL. Extracted DNA: 500 ng. Saliva: Per kit instructions.

LIS Dept Code

Genetics (GEN)

Performing Location(s)

UW-MT	Genetics Attention: Genetics Lab Clinical lab, Room NW220 University of Washington Medical Center 1959 NE Pacific Street Seattle, WA 98195 Tel: 206-598–6429 M–F (7:30 AM–4:00 PM) Fax: 206-616-4584 Lab email: cgateam@uw.edu Tel (EXOME only): 206-543-0459	Faculty Jillian Buchan, PhD, FACMG Runjun Kumar, MD, PhD Regina Kwon, MD, MPH Christina Lockwood, PhD, DABCC, DABMGG Brian Shirts, MD, PhD Abbye McEwen, MD, PhD Colin Pritchard, MD, PhD Vera Paulson, MD, PhD Eric Konnick, MD, MS He Fang, PhD

Frequency

MCC studies are performed weekly once both the primary sample and comparator are received. Results within 2 weeks.

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