1:1 Mix

General Information

Lab Name

1:1 Mix

Lab Code

MIX1P

Epic Name

1:1 Mix Coag Panel

Description

A mixing study is used to evaluate the cause of prolonged Prothrombin Time (PT), PTT and/or Thrombin Time. A 1:1 mix of the patient's plasma and normal pooled plasma is performed and the PT and/or PTT is measured again. If the PT and/or PTT corrects, this suggests a factor deficiency. If the PT and/or PTT does not correct, this suggests presence of an inhibitor. If Thrombin Time is prolonged due to the presence of heparin in the sample, a heparin neutralization step is performed before running the mixing tests. A mixing study interpretation may direct further coagulation testing.

Synonyms

MIX 1:1 (PRO & PTT & TT & FIBCL)

Components

Code	Name
MIX1	1:1 Mix
PTTPT	PTT Patient
PTTNOR	PTT Normal Pool
PTTMIX	PTT 1:1 Mix Immediate
INCMIX	PTT 1:1 Mix Incubated
PROPT	PT Patient
PRONOR	PT Normal Pool
PROMIX	PT 1:1 Mix
MIXCOM	1:1 Mix Comment
TTPAT	Thrombin Time
FIBCL	Fibrinogen
XMIX	1:1 Mix, 2nd tube