Desmoglein 1 and 3 IgG Antibodies (Sendout)
General Information
- Lab Name
- Desmoglein 1 and 3 IgG Antibodies (Sendout)
- Lab Code
- RDES13
- Epic Name
- Desmoglein 1 and 3 IgG Antibodies (Sendout)
- External Test Id
- 0090649
- Description
Ordering Recommendation: Use to monitor disease in patients diagnosed with various pemphigus variants and increased IgG desmoglein 1 and/or IgG desmoglein 3 antibodies; antibody levels correlate with disease activity.
- References
- ARUP Test Information: Desmoglein 1 and Desmoglein 3 (Pemphigus) Antibodies, IgG by ELISA
- Synonyms
- 0090649, Anti-Desmoglein 1, Anti-Desmoglein 3, Desmoglein 1, Desmoglein 3, desmosomal protein antibodies, desmosome antibodies, DSG1, DSG3, DSGAB, endemic pemphigus, fogo selvagem, ICS antibodies, Pemphigus erythematosus, Pemphigus foliaceus, Pemphigus vegetans, Pemphigus vulgaris, RDS13G
- Components
-
Code Name RDESG1 Desmoglein 1 IgG Antibody RDES1R Desmoglein 1 IgG Reference Range RDESG3 Desmoglein 3 IgG Antibody RDES3R Desmoglein 3 IgG Reference Range RDS13I Desmoglein 1 and 3 IgG Interpretation RDS13C Desmoglein 1 and 3 IgG Comment RDS13L Desmoglein 1 and 3 IgG Performing Lab
Interpretation
- Method
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
- Reference Range
- See individual components
- Ref. Range Notes
Reference Range Note: The reference ranges for IgG DSG1 and DSG3 antibody levels have changed effective January 13, 2025, based on replacement of the antibody assay kits with different reagents. The replacement kit performances have been validated and demonstrate analogous results to the former assay kits with different reference ranges.
Desmoglein 1 IgG Antibody:
Normal (Negative): Less than 20 U/mL Increased (positive): Greater than or equal to 20 U/mL Desmoglein 3 IgG Antibody:
Normal (Negative): Less than 20 U/mL Increased (positive): Greater than or equal to 20 U/mL
Ordering & Collection
- Specimen Type
- Blood
- Collection
-
6 mL in RED TOP tube or GOLD SST
- Forms & Requisitions
- ARUP Clinical Information for Immunodermatology Form (optional)
- Handling Instructions
Outside Laboratories:
- Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.
- Optional: Submit a completed ARUP Clinical Information for Immunodermatology Form with the order.
Stability: Refrigerated (preferred): 2 weeks; Frozen: Indefinitely; Ambient: 1 week.
Unacceptable Conditions: Hemolyzed or lipemic specimens, plasma.
- Quantity
-
Requested: 2 mL serum
Minimum: 0.5 mL serum
Processing
- Receiving Instructions
Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.
Sendouts:
- Order ARUP Test: 0090649
- Interfaced: No
- If the (optional) Immunodermatology Form was completed, include it with the ARUP batch sheet.
Stability: Refrigerated (preferred): 2 weeks; Frozen: Indefinitely; Ambient: 1 week.
Unacceptable Conditions: Hemolyzed or lipemic specimens, plasma.
- Misc Sendout
Performance
- Lab Department
- Sendouts(SO)
- Frequency
- Performed: Varies. Reported: 3-9 days from sample receipt at ARUP Laboratories.
- Available STAT?
- No
- Performing Location(s)
-
Sendout ARUP forwards to University of Utah Immunodermatology Laboratory
800-242-2787417 S. Wakara Way
Suite 2151
Salt Lake City, UT 84108Immunodermatology Lab (Direct): 801-581-7139
Billing & Coding
- CPT Codes
- 83516x2
- LOINC
- 94335-7
- Interfaced Order Code
- UOW4786