Inner Ear (Cochlear) Antigen by Western Blot (Sendout)

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General Information

Lab Name
Inner Ear (Cochlear) Antigen by Western Blot (Sendout)
Lab Code
REARWB
Epic Name
Inner Ear (Cochlear) Antigen by Western Blot (Sendout)
External Test Id
F68KD
Description

Test Description: Qualitative test for 68kD (hsp-70) antibodies.

References
  1. Mayo Clinical & Interpretive Information: 68kD (hsp-70) antibodies by Line Blot
Synonyms
anti 68kD Ab, Autoantibody Inner Ear, Cochlear Antibody, F68KD, Heat Shock Protein, HSP 70, HSP-70
Components
Code Name
REARWR Inner Ear Antigen: Anti 68 kD Antibody

Interpretation

Method

Line Blot

Reference Range
See individual components
Interferences and Limitations

This test has been validated using serum samples. The manufacturer has not determined the efficacy of this test when performed on CSF, plasma, joint or pleural fluid specimens.

References
  1. Mayo Clinical & Interpretive Information: 68kD (hsp-70) antibodies by Line Blot

Ordering & Collection

Specimen Type
Blood
Collection

9 mL blood in RED TOP tube or GOLD SST

Handling Instructions

Outside Laboratories: Centrifuge sample and aliquot 2-3 mL serum into a separate plastic vial, leaving room at the top for expansion. Freeze serum at -20°C while awaiting shipment. Transport on dry ice.

Stability: Frozen (preferred): 365 days; Refrigerated: 5 days; Ambient: 48 hours.

Quantity
Requested: 3 mL serum
Minimum: 2 mL serum

Processing

Receiving Instructions

Centrifuge sample and aliquot 2-3 mL serum into a separate plastic vial, leaving room at the top for expansion. Freeze serum at -20°C.

Sendouts:

  • Order Mayo Test: F68KD
  • Interfaced: Yes [Interface: 601; Worksheet: MAFZ]

Stability: Frozen (preferred): 365 days; Refrigerated: 5 days; Ambient: 48 hours.

Misc Sendout

Performance

Lab Department
Sendouts Mayo Lab (FZ)(MAFZ)
Frequency
Performed: Once per week. Reported: 3-8 days from sample receipt at Mayo Clinic Laboratories.
Available STAT?
No
Performing Location(s)
Sendout Mayo forwards to Immco Diagnostics, Inc.
800-533-1710

10 Earhart Dr.
Suite 100
Williamsville, NY 14221

Billing & Coding

CPT Codes
84182
LOINC
43597-4
Interfaced Order Code
UOW2309
Billing Comments

Qualitative test - Positive or Negative

Interpretation: Antibodies to inner ear antigen (68kDa) occur in approximately 70% of patients with autoimmune hearing loss. The antibody tests to this 68kDa antigen parallel with disease activity. In addition, a majority of patients positive for antibodies to 68kDa are responsive to corticosteroid treatment.¹