Factor XIII Qualitative (Sendout)

General Information

Lab Name: Factor XIII Qualitative, Rflx 1:1 Mix (Sendout)
Lab Code: RF13
Epic Name: Factor XIII Qualitative, Rflx 1:1 Mix (Sendout)
External Test Id: 3016927
Description: Ordering Recommendation: Most useful if a severe FXIII deficiency is suspected (<1% of normal activity). Distinguishes between FXIII deficiency and a FXIII inhibitor. Abnormal results should be confirmed with quantitative testing. Severe deficiency may be inherited or acquired (typically due to a factor XIII antibody).

Test Algorithm: If Factor 13 Qualitative has a result of "Lysis," then Factor XIII, 1:1 Mix (Sendout) [RF13MX] will be performed at additional charge.
Synonyms: 3016927, Clot Solubility, F13, Factor 13, Factor XIII, Fibrin Stabilizing Factor, FX13M, FXIII, Urea Solubility
Components

Interpretation

Method

Qualitative Solubility Assay

Reference Range

Female		Male
Age	Range	Age	Range
0-	No Lysis [NOLYS]	0-	No Lysis [NOLYS]

Effective date: 02/01/2024

Ref. Range Notes

Reference Range:

Factor XIII, Qualitative:

No Lysis within 24 hours

Interferences and Limitations

Cautions: False-positive results (lysis) can be caused by heparin (therapy with unfractionated or low molecular weight heparin or contamination from a line), decreased or abnormal fibrinogen, increased fibrinolysis (inherited or acquired fibrinolytic disorders), fibrinolytic drugs, or other factors that affect clot structure or stability.

Ordering & Collection

Specimen Type

Blood

Collection

5 mL BLUE TOP (sodium citrate) tube

Handling Instructions

Outside Laboratories:

Centrifuge for 10 minutes and remove plasma.
Centrifuge the plasma again for another 10 minutes.
Transfer 2 mL platelet-poor plasma into a separate plastic aliquot (minimum 1 mL). Freeze plasma at -20°C.

Stability: Frozen (required): 2 weeks; Ambient: 4 hours; Refrigerated: Unacceptable.

Note: Critical Frozen. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions: Serum, EDTA plasma, clotted or hemolyzed specimens.

Quantity

Requested: 2 mL platelet-poor plasma
Minimum: 1 mL platelet-poor plasma

Processing

Receiving Instructions

UW-MT: Immediately forward specimens to Coagulation Lab for processing. Coag: Double-spin the sample and aliquot 2 mL platelet-poor plasma into a separate plastic aliquot (minimum 1 mL). Freeze plasma at -20°C (place in the UW Sendouts frozen rack).

HMC: Immediately forward specimens to Coagulation Lab for processing. Coag: Double-spin the sample and aliquot 2 mL platelet-poor plasma into a separate plastic aliquot (minimum 1 mL). Freeze plasma at -20°C. Forward to UW-MT for sendout.

UW-NW or Fred Hutch: Centrifuge for 10 minutes and remove plasma. Centrifuge the plasma again for another 10 minutes. Transfer 2 mL platelet-poor plasma into a separate plastic aliquot (minimum 1 mL). Freeze plasma at -20°C. Forward to UW-MT for sendout.

Sendouts:

Order ARUP Test: 3016927.
Interfaced: Yes. [Interface: 602; Department: ARPZ]

Stability: Frozen (required): 2 weeks; Ambient: 4 hours; Refrigerated: Unacceptable.

Note: Critical Frozen. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions: Serum, EDTA plasma, clotted or hemolyzed specimens.

Misc Sendout

Performance

Lab Department

Sendouts ARUP Lab (FZ)(ARPZ)

Frequency

Performed: Sunday through Saturday. Reported: 2-3 days from sample receipt at ARUP.

Available STAT?

Performing Location(s)

Sendout	ARUP Laboratories, Inc. 800-522-2787 500 Chipeta Way Salt Lake City, UT 84108

Billing & Coding

CPT Codes: 85291
LOINC: 3241-7
Interfaced Order Code: UOW3963
Interfaced Result Code: UOW3963