Poliovirus Antibody, Neutralization (Sendout)

General Information

Lab Name
Poliovirus Antibody, Neutralization (Sendout)
Lab Code
RPOLNZ
Epic Name
Poliovirus Ab, Neutralization (Sendout)
External Test Id
FPOLO
Description

Useful For: This is the most appropriate test for confirming poliovirus immune status. The neutralizing serum antibodies detected by this test are specific for individual types of poliovirus.

References
Synonyms
FPOLO, Polio Immune Status Panel, Polio Vaccine Response, Poliovirus (Types 1 and 3) Antibodies
Components

Interpretation

Method

Culture/Neutralization

Reference Range
See individual components
Ref. Range Notes

Reference Values:

Polio 1 Titer: <1:8
Polio 3 Titer: <1:8

The presence of neutralizing serum antibodies (titers of 1:8 up to >1:128) against polioviruses implies lifelong immunity. Some persons without detectable titers (<1:8) may also be immune as demonstrated by elicitation of a secondary-type serum antibody response upon rechallenge with live polio vaccine.

References

Ordering & Collection

Specimen Type
Blood
Collection

3 mL blood in RED TOP tube or GOLD SST

Handling Instructions

Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum while awaiting shipment. Transport with a cold pack.

Stability: Refrigerated (preferred): 14 days; Frozen: 30 days; Ambient: 5 days.

Quantity
Requested: 1 mL serum
Minimum: 0.5 mL serum

Processing

Receiving Instructions

Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.

Sendouts:

  • Order Mayo Test: FPOLO.
  • Interfaced: Yes [Interface: 601; Worksheet: MARF]

Stability: Refrigerated (preferred): 14 days; Frozen: 30 days; Ambient: 5 days.

Misc Sendout

Performance

Lab Department
Sendouts Mayo Lab (RF)(MARF)
Frequency
Performed: Monday, Thursday. Report Available: 1-10 days from sample receipt at Mayo Clinic Labs.
Available STAT?
No
Performing Location(s)
Sendout Mayo forwards to Quest Diagnostics Nichols Institute
800-533-1710

33608 Ortega Highway
San Juan Capistrano, CA 92675

Billing & Coding

CPT Codes
86382x2
LOINC
41506-7
Interfaced Order Code
UOW2249