S. pneumoniae IgG Antibody, 23 Serotypes (Sendout)
General Information
- Lab Name
- S. pneumoniae IgG Antibody, 23 Serotypes (Sendout)
- Lab Code
- RSP23
- Epic Name
- S pneumoniae IgG Antibodies, 23 Serotypes (Sendout)
- External Test Id
- PN23M
- Description
Useful For:
- Assessing the IgG antibody response to active immunization with nonconjugated, 23-valent pneumococcal vaccines
- Assessing the IgG antibody response to active immunization with conjugated 13-valent, 15-valent and 20-valent pneumococcal vaccines
- Determining the ability of an individual to produce an antibody response to polysaccharide antigens, as part of the evaluation for humoral or combined immunodeficiencies
Ordering Guidance: This test is the preferred test for patients previously tested for Streptococcus pneumoniae serotypes (as part of follow up testing or part of pre/post vaccine assessment).
- Synonyms
- PN23, PN23M, Pneumococcal Antibody (IgG) 23 Serotype Panel, Strep Pneumoniae Antibody, Strep Vaccine, Streptococcus Pneumoniae
- Components
-
Code Name RST1 Serotype 1 (1) RST2 Serotype 2 (2) RST3 Serotype 3 (3) RST4 Serotype 4 (4) RST5 Serotype 5 (5) RST8 Serotype 8 (8) RST9N Serotype 9N (9) RST12F Serotype 12F (12) RSTY14 Serotype 14 (14) RST17F Serotype 17F (17) RST19F Serotype 19F (19) RSTY20 Serotype 20 (20) RST22F Serotype 22F (22) RST23F Serotype 23F (23) RST6B Serotype 6B (26) RST10A Serotype 10A (34) RST11A Serotype 11A (43) RST7F Serotype 7F (51) RST15B Serotype 15B (54) RST18C Serotype 18C (56) RST19A Serotype 19A (57) RST9V Serotype 9V (68) RST33F Serotype 33F (70) RSP23I S. pneumoniae IgG Antibody, 23 Serotypes Interpretation
Interpretation
- Method
Microsphere Photometry
- Reference Range
- See individual components
- Interferences and Limitations
Cautions:
The humoral immune response to Streptococcus pneumoniae is age dependent and the database of IgG antibody concentrations to different serotypes is incomplete.
Protective concentrations of IgG antibodies, or those required to prevent infection from S pneumoniae, have not been defined for any serotype.
Quantitation of the IgG antibody response to pneumococcal serotypes does not provide any information on the functional capacity of the serotype-specific antibodies generated (opsonization efficiency).
Ordering & Collection
- Specimen Type
- Serum
- Collection
-
3 mL blood in RED TOP tube or GOLD SST
Unacceptable: Any other tube type
- Handling Instructions
Outside Laboratories: Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum while awaiting shipment. Transport with a cold pack.
Stability: Refrigerated (preferred): 21 days; Frozen: 21 days; Ambient: Unacceptable.
- Quantity
-
Requested: 0.5 mL serum
Minimum: 0.4 mL serum
Processing
- Receiving Instructions
Centrifuge sample and transfer serum to a separate plastic vial. Refrigerate serum.
Sendouts:
- Order Mayo Test: PN23M
- Interfaced: Yes [Interface: 601; Worksheet: MARF]
Stability: Refrigerated (preferred): 21 days; Frozen: 21 days; Ambient: Unacceptable.
- Misc Sendout
Performance
- Lab Department
- Sendouts Mayo Lab (RF)(MARF)
- Frequency
- Performed: Monday - Friday. Report Available: 4 - 6 days.
- Available STAT?
- No
- Performing Location(s)
-
Sendout Mayo Clinic Laboratories (Superior Drive)
800-533-17103050 Superior Drive NW
Rochester, MN 55901
Billing & Coding
- CPT Codes
- 86581
- LOINC
- 42366-5
- Interfaced Order Code
- UOW2392