IA-2 Antibody (Sendout)

single page view

General Information

Lab Name
IA 2 Antibody (Sendout)
Lab Code
RIA2A
Epic Name
IA-2 Antibody (Sendout)
External Test Id
3001499
Description

Ordering Recommendation: Most useful to establish autoimmune etiology in previously diagnosed type 1 DM. Do not use to differentiate type 1 DM from type 2 DM, for most cases. Many cases of autoimmune diabetes mellitus are associated with specific autoantibodies, including Insulin Antibody (Sendout) [RINSG], GAD65 Ab Assay (Sendout) [RGD65], IA-2 Antibody (Sendout) [RIA2A], and Zinc Transporter 8 Antibody (Sendout) [RZNT8A]. Presence and persistence of two or more of these autoantibodies predicts clinical DM. When evaluating for autoimmune diabetes mellitus, perform testing for at least two autoantibodies (typically, GAD65 in combination with another of the above autoantibody tests).

      References
      Synonyms
      3001499, Anti-IA2 Antibodies, Beta-Cell Autoantibody to IA-2, IA2, ICA-512, Insulinoma Associated 2 Antibody, Islet cell antigen - 512, Tyrosine Phosphatase-Like Protein Antibodies
      Components
      Code Name
      RIA2AN IA 2 Antibody

      Interpretation

      Method

      Quantitative Enzyme-Linked Immunosorbent Assay

      Reference Range
      See individual components
      Ref. Range Notes
      Reference Interval: 0.0-7.4 Units/mL
      References

      Ordering & Collection

      Specimen Type
      Blood
      Collection

      3 mL blood in GOLD SST or RED TOP tube

      Handling Instructions

      Outside Laboratories: Centrifuge sample and aliquot serum to a separate plastic vial. Refrigerate serum while awaiting shipment. Transport with a cold pack.

        Stability: Refrigerated (preferred): 1 week; Frozen: 2 months; Ambient: 24 hours.

          Unacceptable Conditions: Plasma, specimens submitted in frozen SST tubes. Grossly hemolyzed, icteric, or lipemic specimens.

          Quantity
          Requested: 0.5 mL serum
          Minimum: 0.35 mL serum

          Processing

          Receiving Instructions

          Centrifuge sample and aliquot serum to a separate plastic vial. Refrigerate serum.

            Sendouts:

            • Order ARUP Test: 3001499
            • Interfaced: Yes [Interface: 602; Department: ARPR]

            Stability: Refrigerated (preferred): 1 week; Frozen: 2 months; Ambient: 24 hours.

            Unacceptable Conditions: Plasma, specimens submitted in frozen SST tubes. Grossly hemolyzed, icteric, or lipemic specimens.

            Misc Sendout

            Performance

            Lab Department
            Sendouts ARUP Lab (RF)(ARPR)
            Frequency
            Performed: Monday, Wednesday, Friday. Reported: 2-10 days from sample receipt at ARUP Laboratories.
            Available STAT?
            No
            Performing Location(s)
            Sendout ARUP Laboratories, Inc.
            800-522-2787

            500 Chipeta Way
            Salt Lake City, UT 84108

            Billing & Coding

            CPT Codes
            86341
            LOINC
            56718-0
            Interfaced Order Code
            UOW3771