Roche Platform Transition

This page compares reference ranges between the Roche and Beckman platforms for the selected category of tests. For a description of the transition from the Beckman to Roche automated chemistry platform, please see the Chemistry and Immunoassay Beckman to Roche Transition Guideline.

All BMP Liver Kidney Lipids Endocrine Tumor Marker Cardiac Misc Drugs Heme

Method Comparison

The comparison table contains the following columns:

  • Trendable?: Indicates whether both methods use the same component code and results are trendable in Epic.
  • Bias: The average absolute difference between Roche and Beckman results. A positive value means Roche results are higher on average.
  • Percent Bias: Blue shading and bars extending left indicate negative bias (Beckman higher on average); orange shading and bars extending right indicate positive bias (Roche higher on average). Longer bars indicate greater magnitude.
  • Slope: The slope of the linear regression of Roche onto Beckman, representing proportional bias between the methods. “Not comparable” indicates that the methods were too poorly correlated for direct patient-result comparison.
  • R2 (Coefficient of Determination): How closely the regression fits the paired results.

These data can help when comparing results across platforms, but should not be used to convert a result directly from one method to the other.

Test Name Beckman Roche Trendable? Bias Percent Bias Slope Coefficient of Determination (R2)
Albumin ALB ALB ✅ 0.122 g/dL 3.14% 0.965 0.992
Alkaline Phosphatase (Total) ALK ALK ✅ 1.11 U/L 0.72% 1.01 0.9967
ALT ALT ALTRD ❌ 15.916 U/L 33.30% 1.307 0.9896
Ammonia, Plasma PLNH3 PNH3RD ❌ Not comparable
AST AST ASTRD ❌ 26.77 U/L 25.01% 1.233 0.9964
Direct Bilirubin BILD BILDRD ❌ 0.2022 mg/dL 7.84% 1.098 0.9701
Gamma Glutamyl Transferase GGT GGT ✅ 16.952 U/L 17.68% 1.308 0.9641
Total Bilirubin BIL BILRD ❌ -0.3113 mg/dL -6.30% 0.927 0.9706
Total Protein TP TPRD ❌ -0.365 g/dL -5.61% 1.022 0.9228

Reference Ranges

Name
Beckman
Roche
Albumin
Name: Albumin
Mnemonic: ALB
Units: g/dL
Method Code: default
Female Male
AgeRange AgeRange
0- 3.9-5.2 0- 3.9-5.2
Effective date: 09/14/2026
Name: Albumin
Mnemonic: ALB
Units: g/dL
Method Code: EVPUR1
Female Male
AgeRange AgeRange
0- 3.9-5.2 0- 3.9-5.2
Effective date: 02/20/2026
Alkaline Phosphatase (Total)
Name: Alkaline Phosphatase (Total)
Mnemonic: ALK
Units: U/L (units differ between platforms)
Method Code: default
Female Male
AgeRange AgeRange
0- 35-104 0- 40-129
Effective date: 09/14/2026
Name: Alkaline Phosphatase (Total)
Mnemonic: ALK
ALT
Name: ALT (Beckman)
Mnemonic: ALT
Units: U/L
Method Code: default
Female Male
AgeRange AgeRange
0- 7-33
0-49y 10-64
50y- 10-48
Effective date: 03/01/2015
Name: ALT (Roche)
Mnemonic: ALTRD
Units: U/L
Method Code: default
Female Male
AgeRange AgeRange
0- 0-43 0- 0-63
Effective date: 09/02/2026
Ammonia, Plasma
Name: Ammonia, PLASMA (Beckman)
Mnemonic: PLNH3
Units: mcg/dL
Method Code: default
Female Male
AgeRange AgeRange
1d-13d 110-180 1d-13d 110-180
14d-29d 95-155 14d-29d 95-155
1m-11y 35-85 1m-11y 35-85
12y- 0-65 12y- 0-65
Effective date: 03/01/2015
Name: Ammonia, Plasma (Roche)
Mnemonic: PNH3RD
Units: mcg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- 0-51 0- 0-51
Effective date: 09/02/2026
AST
Name: AST (Beckman)
Mnemonic: AST
Units: U/L
Method Code: default
Female Male
AgeRange AgeRange
0- 9-38 0- 9-38
Effective date: 03/01/2015
Name: AST (Roche)
Mnemonic: ASTRD
Units: U/L
Method Code: default
Female Male
AgeRange AgeRange
0- 0-35 0- 0-50
Effective date: 09/02/2026
Direct Bilirubin
Name: Direct Bilirubin (Beckman)
Mnemonic: BILD
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- 0.0-0.3 0- 0.0-0.3
Effective date: 03/01/2015
Name: Direct Bilirubin (Roche)
Mnemonic: BILDRD
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0- 0.0-0.4 0- 0.0-0.4
Effective date: 09/02/2026
Gamma Glutamyl Transferase
Name: Gamma Glutamyl Transferase
Mnemonic: GGT
Units: U/L
Method Code: default
Female Male
AgeRange AgeRange
0- 0-50 0- 0-59
Effective date: 09/14/2026
Name: Gamma Glutamyl Transferase
Mnemonic: GGT
Units: U/L
Method Code: FMPRO1
Female Male
AgeRange AgeRange
0- <51 0- <60
Effective date: 03/12/2026
Total Bilirubin
Name: Total Bilirubin (Beckman)
Mnemonic: BIL
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0-29d 0.2-1.3 0-29d 0.2-1.3
1m- 0.2-1.3 1m- 0.2-1.3
Effective date: 03/01/2015
Name: Total Bilirubin (Roche)
Mnemonic: BILRD
Units: mg/dL
Method Code: default
Female Male
AgeRange AgeRange
0-29d 0.0-1.1 0-29d 0.0-1.1
1m- 0.0-1.1 1m- 0.0-1.1
Effective date: 09/02/2026
Total Protein
Name: Total Protein (Beckman)
Mnemonic: TP
Units: g/dL
Method Code: default
Female Male
AgeRange AgeRange
0- 6.0-8.2 0- 6.0-8.2
Effective date: 03/01/2015
Name: Total Protein (Roche)
Mnemonic: TPRD
Units: g/dL
Method Code: default
Female Male
AgeRange AgeRange
0- 6.4-8.3 0- 6.4-8.3
Effective date: 09/02/2026